Personally I don’t think so. In both league and dota I feel its best to utilize moving the camera and map clicks. But I don’t know if its a recent change but the camera seems really close in Dota now. So i lock on with F1 when I’m chasing but while I’m being chased I usually just click once on the map to get a general sense of where I’m running too and then start looking for places to go while the hero is moving.

In league though I look at the map so much it doesn’t seem to matter if I lock it or not. But I still like moving the camera around.